GMP Technician (50%) / Lab Technician (20%)

70%, Zurich, permanent The Wyss Zurich is a joint accelerator of the ETH Zurich and the University of Zurich, which was made possible by a generous donation from the Swiss entrepreneur and philanthropist Dr. hc. mult. Hansjörg Wyss. The mission of Wyss Zurich is to drive the clinical translation and technology transfer of outstanding scientific discoveries into new therapies for patients and breakthrough innovations in the emerging fields of Regenerative Medicine and Robotics, and to promote hybrid technologies in these fields. Wyss Zurich brings together some of the world’s leading experts to form multidisciplinary teams, pooling their knowledge and expertise. For further information: www.wysszurich.uzh.ch.

Project background

The goal of the MUS.I.C. Project (www.music2020.ch) is to develop a novel tissue-regenerative approach to treat urinary incontinence of female patients, using autologous muscle precursor cells. This includes first, the conduct of the first-in-man trial to evaluate safety (tolerability and efficacy) and second, the optimization of the advanced-therapy medicinal product towards totally xeno-free and facilitated manufacturing, as well as a novel injection technique. The project is funded by the European Horizon 2020 program and is led by the University of Zurich and Laboratory for Urologic Oncology and Stem Cell Therapy.

Job description

We are looking for an ambitious and flexible GMP/Research Technician to support the production of an autologous cell product for use in a fist-in-human clinical trial.

The position will be clearly divided between GMP (50%) and Lab (20%) support. You will be able to join a young and dynamic start-up team and will be working in a grade B clean room (in collaboration with Wyss Zurich, facility at Moussonstrasse) to support in the production of muscle precursor cells from patient biopsies in a GMP compliant manner. Furthermore, you will support the laboratory in Schlieren (Wagistrasse) in daily routine tasks, such as lab management and organization, as well as support of ongoing research projects which aim to further improve the therapy being developed. Finally, as the project is being established towards a spin-off, there is a possibility to join this newly founded company in the near future. Please note that the contract is issued by the University of Zurich.

Main Tasks 

• GMP-compliant cell production in the GMP cleanroom facility (primary cell production, analysis according to current GMP regulations, coordination) 


• Clear and structured data organization for precise documentation


• General lab support: routine and common daily tasks (mammalian cell culture, various analytical assays, etc.), lab organization and coordination (e.g. ordering)

Your profile

• Education level: Biological lab technician or Bachelor’s degree in Biology, Biotechnology or a similar field (note: Candidates holding a PhD degree cannot be considered)


• Strong experience in mammalian cell culture is mandatory
  


• Open and ready to work in GMP cleanroom class B; previous GMP experience highly desirable


• Precise working method, attention to detail and ability to work under time pressure


• Flexible working times, willingness to commute between the lab (Schlieren) and GMP facility (ZH city)


• Communication skills in English and German required, French desirable