Job Detail

PhD Student Position in

Neuroimmunology/Brain Barriers Research
at the Theodor Kocher Institute, University of Bern

In the group of Prof. Britta Engelhardt, there is an opening for a qualified and highly motivated individual aiming to pursue a PhD thesis in the field of neuroimmunology.

TasksThe Swiss National Science Foundation funded project entitled "Brain Barriers ID: Identifying and detailing the molecular mechanisms regulating the integrity and immune function of the brain barriers" aims to specifically address the cellular and molecular mechanisms of the migration of different T cell subsets across the brain barriers during immunosurveillance and neuroinflammation, employing
in vitro blood-brain barrier and transgenic mouse
in vivo models combined with advanced live cell imaging technologies. The project offers a translational aspect by making use of multiple sclerosis-patient sourced stem-cell derived
in vitro brain barrier models to ID the mechanisms regulating brain barriers permeability versus T-cell diapedesis in man.RequirementsThe successful candidate has preferentially a master degree in the life sciences, a dedicated interest in brain barrier research and immune cell trafficking, using in vitro and in vivo models and high-end microscopy techniques. The candidate is expected to have a high motivation in pursuing a team-oriented research effort.We offerThe position is available from September 1st, 2020 on. The TKI offers an international state-of-the-art laboratory environment. The PhD student will be enrolled in the interfaculty Graduate School for Cellular and Biomedical Sciences at the University of Bern (www.gcb.unibe.ch). Excellent training possibilities will additionally be available through the swissuniversities funded ProDoc "Cell Migration"(www.cell-mig.ch) and the Microscopy Imaging Center (www.mic.unibe.ch). In addition, the PhD student will be interacting with numerous national and international collaboration partners in this project.Applications including a CV, information on educational background and experience, a meaningful motivation letter and 2 references should be send to:

Prof. Britta Engelhardt, Theodor Kocher Institute, University of Bern, Freiestr. 1, CH-3012 Bern, Switzerland.
E-Mail:
bengel@tki.unibe.ch,
Homepage:www.tki.unibe.ch

www.unibe.ch

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