The Paul Scherrer Institute PSI is the largest research institute for natural and engineering sciences within Switzerland. We perform cutting-edge research in the fields of matter and materials, energy and environment and human health. By performing fundamental and applied research, we work on sustainable solutions for major challenges facing society, science and economy. PSI is committed to the training of future generations. Therefore about one quarter of our staff are post-docs, post-graduates or apprentices. Altogether PSI employs 2100 people.
For the Center of Radiopharmaceutical Sciences in the Pharmacology Group we are looking for aPhD StudentDevelopment of ovarian cancer stem cell-directed radioimmunotherapy using Auger-electron and alpha-particle emittersYour tasksTargeting ovarian cancer stem cells CSCs with anti-L1CAM antibodies offers a new strategy for CSC therapy. In this study you will:
Analyse if there are more CSC populations in ovarian cancer that express L1CAM.
Analyse which CSC populations are abundant in patient-derived tumours and ascites
Analyse the mechanisms that lead to the radioresistance by L1CAM expression in CSCs
The final goal is to development an antibody-based targeted therapy of CSCs
The candidate can expect a full-time position in a highly motivated, research group that offers an excellent research environment. The work place is located at the Paul Scherrer Institut and the Department of Biomedicine, University Hospital Basel.Your profile
We are looking for a candidate with a Master’s degree (or close to completion) in biology, biochemistry, pharmaceutical sciences, life sciences or an equivalent field
Proficient oral and written English skills are expected
A background in cell biology, molecular biology and animal experimentation is beneficial
We offerOur institution is based on an interdisciplinary, innovative and dynamic collaboration. You will profit from a systematic training on the job, in addition to personal development possibilities and our pronounced vocational training culture. If you wish to optimally combine work and family life or other personal interests, we are able to support you with our modern employment conditions and the on-site infrastructure.
For further information please contact Dr Jürgen Grünberg, phone +41 56 310 28 48.
Please submit your application online by 30 April 2020 (including addresses of referees) for the position as a PhD Student (index no. 2222-00).
Paul Scherrer Institut, Human Resources Management, Silja Giacomini-Diebold, 5232 Villigen PSI, Switzerlandwww.psi.chApply now
