Behind every presentation of each product sold by Roche is the involvement of Pharma Global Technical Operations (PT). Starting with Phase I of the development process and continuing through to product maturity, PT makes medicines at sites around the world and includes more than 10 000 employees worldwide.
Global Technical Development (PTD) is an organization of over two thousand people globally that are integral for the mission of Roche to develop meaningful medicines for patients. Therefore, PTD actively collaborates and develops creative technical solutions to bridge early-stage, late-stage and commercial product needs. The mandate of the group is, to reliably deliver the pipeline and supply quality products to patients. The group excels in its work through innovation, teamwork, dedication, and mutual respect and contributes every single day, continuously improving what it does.
Small Molecules Technical Development (PTDC) brings a broad range of experience across drug substance (DS), drug product (DP), analytical sciences and manufacturing S&T, and collaborates closely with key partners in the departments Research and Early Development (pRED / gRED), Small Molecules (PTC) and PTD. PTDC is responsible for late stage technical development of our small molecules pipeline, manufacture of DS and DP for clinical studies and Manufacturing Science and Technology (MSAT) across our small molecules manufacturing network.
The Analytical Development department is part of Global Technical Development and responsible for analysing drug substances and dosage forms of small molecule development products. The Hyphenated & Special Technologies section provides key scientific customer support with Mass Spectrometry, Separation Sciences and innovative special technologies.
As Group Leader you are responsible for the following main tasks:
You will give Mass Spectrometry (MS) and Special Technologies support for small molecule/new modalities projects in close collaboration with process development stakeholders (e.g. process development chemists and pharmacists, product manufacturers, Regulatory Affairs, QA and analytical partners for formulation development, IPC, active substances). This includes qualitative and quantitative analysis like for example trace determination of Extractables & Leachables, structure elucidation of small molecules and oligonucleotides, trace determination of genotoxic impurities or elemental impurities
You will lead and develop employees according to Roche Leadership Commitments, demonstrating Servant Leadership Behaviors and encouraging highly motivated employees to achieve courageous goals hence demonstrating the Roche leadership principles
You will oversee (and be involved in) experimental laboratory work with a team of technicians
You will support efficient "time to market"-driven analytics for pharmaceutical development products and licensed products
You will support troubleshooting activities for commercial products incl. Small Molecules, Oligos and Biologics
You will support the maintenance of the laboratory infrastructure (including high-resolution MS instruments) as well as GxP-, SHE- as well as personnel development trainings for team members
You will provide support for the section head and for the entire organization in developing and implementing departmental strategies and goals (revising and authoring SOPs governing the organisation of and procedures in the department)
Who you are:
We are looking for a candidate that holds a Doctorate degree in chemistry, pharmacy, food chemistry or equivalent or a Master degree with significant background in the relevant field. That would be hands-on experience in mass spectrometry coupled with chromatography (e.g. LC-MS and GC-MS). In addition, experience in solving analytical challenges by application of various MS techniques would be a plus.
In addition, you fulfill the following requirements:
Preferably, experience in the pharmaceutical industry
Excellent people leader and teammate
Working style motivated by team focus, flexibility, pragmatism, responsibility and innovation
Excellent organisational skills, self-driven, efficient and reliable attitude
Excellent command of written and spoken English and fluent in German
Have we sparked your interest? Apply now!
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