Job Detail

Who We Are

At Roche, over 90,000 people across 150 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche's Pharma Research and Early Development Informatics team is the bridge between digital technology and science. We help drive medical innovation and are integral to the realisation of truly Personalised Healthcare and the development of innovative treatments for our patients.

Digital tools, such as smartphones or wearables, can now continually measure and collect vital health information – or “Digital Biomarkers” – from Multiple Sclerosis (MS) patients. Digital Biomarkers are changing how future medicines will be developed and could lead to more personalised use of new medications that will transform the lives of MS patients. Advances in wearable devices, such as phones, watches, textiles or delivery devices, which track a patient’s vital signs and monitor for symptoms, all have the potential to vastly accelerate clinical development.

Roche is dedicated to creating community- and regulator-accepted endpoints and outcomes that will redefine the measurement of MS disease progression, and thereby change the understanding of MS as a disease. We’re seeking future-thinking innovators who know how to apply their expertise to help transform MS.

The Position

As a Digital Biomarker Data Analysis Expert with focus on Passive Monitoring, Biomechanics and Gait - Multiple Sclerosis you will:

Tasks & Responsibilities:

• Work on large amounts of sensor data from smartphones, wearables and other devices collected during the daily life of participants in Roche clinical studies


• Develop robust algorithms to infer different activities of daily life from the sensor data


• Develop robust algorithms to quantify movements in different activities of daily life


• Use the data produced by your algorithms to help deepen the understanding of how impairments induced by neurological diseases impact the daily life of a patient


• Drive the understanding of the data analysis results by clinical development programs through the development of compelling narratives and presentation


• Write manuscripts for peer-reviewed journal articles to establish the biological, clinical and patient relevance of data collected in novel digital biomarker approaches


• Drive the review process of these journal articles with scientific, clinical and other experts


• Contribute to the improvement and automation of the data processing and analysis pipeline across programs

This is a temporary position.

Who You Are

You’re someone who wants to influence your own development. You’re looking for a company where you have the opportunity to pursue your interests across functions and geographies. Where a job title is not considered the final definition of who you are, but the starting point. If you have these qualifications, we look forward to receiving your application:

• Very good university degree in mathematics, statistics, engineering, natural science or informatics


• 5+ year of  experience with biomechanical (e.g. movement data such as accelerometer, gyroscope) data collected in neurological diseases


• Strong experience with analyzing and visualizing large data sets


• Strong experience with analysing continuous sensor data streams; experience with speech, ECG, and/or - EEG data would be highly desirable


• Excellent analytical, communication and writing skills


• Track record of writing compelling publications in high impact, peer reviewed journals


• Experience with deep learning and other machine learning techniques


• Profound knowledge in Python, R or similar software packages/languages


• Self-starting team player with strong and collaborative “can-do” attitude


• Highly efficient user of MS Office, excellent PowerPoint slide writer


• Excellent in English; excellent writing skills

Should you have these additional nice-to-have skills, you are the ideal team member we are searching for:

• Experience in a scientific role in the pharmaceutical industry, ideally with clinical studies


• Experience with software development processes and big data infrastructures


• Previous hands-on clinical experience with Multiple Sclerosis. Experience in Parkinson’s Disease, Autism Spectrum Disorder, Schizophrenia, neuromuscular atrophies/dystrophies is also interesting


• Good understanding of regulatory frameworks and compliance implications (e.g. GxP, GDPR)


• Experience with remote patient monitoring


• Experience in experimental/clinical study design

If you are proud of contributing and feel you have the dedication to teamwork and innovation that we are seeking, then Roche is the organization for you. Every role at Roche plays a part in making a difference to patients’ lives. If you want work in a passionate team, make your mark & improve lives, apply now.

Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be. We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

If you have questions, please check our FAQs and videos on careers.roche.ch/faq.

Helpful links illustrating recent work in our Digital Biomarker Programme team
 

Multiple Sclerosis:
floodlightopen.com

www.btcalgary.ca/video/iframe/2226196965001/SkX1bBGY/5838106745001

www.roche.com/de/media/releases/med-cor-2018-10-02.htm

www.futuremedicine.com/doi/pdf/10.2217/nmt-2017-0054

www.roche.com/media/store/releases/med-cor-2017-10-27.htm

www.youtube.com/watch?v=6BPS5tl2RRc

www.youtube.com/watch?v=k8XulS3IxBc

Digital Biomarker programme overview:
isctm.org/public_access/Autumn2018/Presentation/Gossens-Aut18.pdf

Schizophrenia:
isctm.org/public_access/Autumn2018/PDFs/Umbricht-Poster.pdf

Parkinson’s Disease:
onlinelibrary.wiley.com/doi/full/10.1002/mds.27376

Huntington’s Disease:
curehd.blogspot.com/2018/03/roche-gears-up-for-pivotal-phase-3.html