Job Detail

Purification Development Technician/Assistant

Inseriert am: 20.08.2018

  • Bioanalytical Project Coordinator

  • Research Technician/Assistant

  • Clinical Operations Manager (based in Basel)

  • QA Validation Specialist

  • Clinical Document Specialist (based in Basel)

  • Purification Development Technician/Assistant

  • Clinical Database Developer

  • Head of Purification & Drug Product Development


Purification Development Technician/Assistant


CAREER OPPORTUNITY

Purification Development Technician/Assistant


Novimmmune SA is a Swiss drug discovery and development company located in Geneva and focused on the creation of antibody-based drugs for the targeted treatment of inflammatory diseases, immune-related disorders, and cancer.

Novimmune has an exciting opportunity for a Research Technician/Assistant position in Downstream Process and DrugProduct Development team. The selected candidate will work under the direct supervision of the Downstream Process and Drug Product Development team and will interact closely with other members of the Bioprocessing R&D Department.


Description of activities:



  • Perform scale-down model qualification and process characterization studies

  • Execute antibody purification at lab scale to supply material  for in-house  studies

  • Perform lab scale evaluations to assess process capabilities

  • Support equipment qualification activities

  • Develop and optimize downstream processes

  • Record data in a timely manner following the internal requirements

  • Contribute to process transfer to external partners

  • Provide support for writing and reviewing documentation when required (protocols, reports, SOPs)


Skills and competencies:



  • Master’s Degree in Biotechnology, Biology, Biochemistry, Chemistry or equivalent with at least 6 months experience in protein purification or Technical degree with a significant experience in protein purification (> 3 years)

  • Hands-on industrial experience of purification processes for proteins (especially antibodies) (e.g., column packing, ion exchange/mixed mode & Protein A affinity chromatography and ultrafiltration/diafiltration) in a pharmaceutical / biotech environment

  • Experience of use of ÄKTA systems (e.g. Purifier, Avant, Pilot) and Unicorn Software ( equivalent automated systems) is a must

  • Experience in process validation activities including scale down model qualification and process characterization studies would be a plus

  • Previous experience in development of downstream processes (including the use of a DoE software) would be an advantage

  • Good knowledge of analytical techniques (e.g. SDS-PAGE, IEF, HPLC)

  • Able to interpret results, identify potential improvements and perform troubleshooting

  • Willing to work approximately 80% of the time in the lab

  • Proficiency in use of Microsoft Office software including Excel, Word and Powerpoint

  • Able to perform routine experiments following internal procedures and pre-established protocols

  • Able to work both autonomously and within a team (depending on the projects)

  • Good communication skills

  • Self-organized and ability to perform the expected work according to project timelines

  • Meticulous

  • Team player

  • Ability to work in an English environment

  • Proficiency in spoken English


If your profile matches the above description, please send us your CV and motivation letter in English under the reference DSP-T1 to the following email address: hr-recruitment@novimmune.com

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